ARISTOLOCHIC ACID
Aristolochic acid I
CAS: 313-67-7;67123-64-2
Molecular Formula: C17H11NO7
ARISTOLOCHIC ACID - Names and Identifiers
ARISTOLOCHIC ACID - Physico-chemical Properties
| Molecular Formula | C17H11NO7 |
| Molar Mass | 341.27 |
| Density | 1.3162 (rough estimate) |
| Melting Point | 260 °C |
| Boling Point | 476.92°C (rough estimate) |
| Flash Point | 326°C |
| Solubility | Soluble in ethanol, chloroform, ether, acetone, acetic acid, aniline and alkali, slightly soluble in alkali, almost insoluble in benzene and carbon disulfide. |
| Vapor Presure | 5.24E-16mmHg at 25°C |
| Appearance | Brown crystal |
| Color | yellow |
| pKa | 2.99±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4500 (estimate) |
| MDL | MFCD00004996 |
| Physical and Chemical Properties | Yellow crystalline powder, soluble in methanol, ethanol, derived from Aristolochia root (black wood),(North Aristolochia highest content). |
ARISTOLOCHIC ACID - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R68 - Possible risk of irreversible effects R36/37/38 - Irritating to eyes, respiratory system and skin. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R45 - May cause cancer |
| Safety Description | S7 - Keep container tightly closed. S35 - This material and its container must be disposed of in a safe way. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S53 - Avoid exposure - obtain special instructions before use. |
| UN IDs | UN 1544 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | CF3325000 |
| HS Code | 29329990 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 38.4, 70.1, 82.5, 74.0 i.v.; 55.9, 106.1, 203.4, 183.9 orally (Mengs) |
ARISTOLOCHIC ACID - Reference
| Reference Show more | 1. Yin Hao, Chen Yunji, Tian Xiaoting, etc. Analysis of chemical constituents of Aristolochia bolus decoction based on HPLC-Q-TOF/MS [J]. World Science and Technology: modernization of traditional Chinese medicine, 2019(7). 2. Shao Zhuying, Pan Jinhuo, Zhang Yueyu, Jiang Zhitao, Wang Xue, Feng Xingyue, wang Jianchun. Protective effect of 6-gingerol on aristolochic acid A- induced injury in HK-2 renal tubular epithelial cells [J]. Chinese traditional medicines, 2020,42(10):2744-2747. 3. [IF = 7.514] Huihuang Xiong et al."Thermosensitive and magnetic atherosclerotic polymers for selective recognition and extraction of aristolochic acid I." Food Chem. 2022 Mar;372:131250 4. [IF = 7.46] Wu et al Si-Qi. "Gold nanoclusters-based paper sensor for the visualized detection of neonatal aristolochic acids." Sensor Actuat B- Chem. 2021 Aug;340:129792 5. [IF = 4.171] Chengni Jin et al."The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy."Food Funct. 2020 Sep;11(9):7456-7467 6. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 |
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Multiple SpecificationsSpot supply
Product Name: Aristolochic acid A Visit Supplier Webpage Request for quotationCAS: 313-67-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Aristolochic Acid Visit Supplier Webpage Request for quotationCAS: 313-67-7
Tel: +86-(0)731-84213302
Email: sales@staherb.cn
Mobile: +86 13875855783
QQ: 484702402
WhatsApp: +86 18374838656
Linkedin: +86 18374838656
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